药学系
研究成果

[1] Liang T, Wu X, Wang L, Ni Z, Fan Y, Wu P, Wang H, Niu Y, Huang H. Clinical significance and diagnostic value of QPCT, SCEL and TNFRSF12A in papillary thyroid cancer. Pathology Research and Practice, 2023; 245(73):154431.

[2] Wu X, Ni Z, Song T, Lv W, Chen Y, Huang D, Xie Y, Huang W, Niu Y. C-terminal truncated HBx facilitates oncogenesis by modulating cell cycle and glucose metabolism. International Journal of Molecular Sciences, 2023; 24, 5174.

[3] Li S, Huang Y, Yu L, Ji X, Wu J. Impact of the Cannabinoid System in Alzheimer's Disease. Curr Neuropharmacol, 2023;21(3):715-726.

[4] Li S, Ji X, Gao M, Huang B, Peng S, Wu J. Endogenous Amyloid-Formed Ca2+-permeable Channels in Aged 3XTg AD Mice. Function ,2023; 26;4(4): zqad025.

[5] Pu K, Qiu J, Tong Y, Liu B, Cheng Z, Chen S, Ni WX, Lin Y, Ng KM. Integration of Non-targeted Proteomics Mass Spectrometry with Machine Learning for Screening Cooked Beef Adulterated Samples. J.  Agric. Food Chem, 2023; 71(4): 2173-2182.

[6] Li X, Li J, Hong P, Ni WX, Luo B. Rapid detection of urine chloride enabled by ion exchange in hydrophilic lead halide perovskite nanocrystals. Anal. Methods, 2023; 15: 2318-2325.

[7] Jiang L, Huang H, Shi X, Wu J, Ye J, Xu Q, Fang S, Wu C, Luo R, Lu C, Liu D. Biocontrol microneedle patch: A promising agent for protecting citrus fruits from postharvest infection. Pharmaceutics, 2023; 15, 1219.

[8] Pan M, Lu C, Zhang W, Huang H, Shi X, Tang S, Liu D. Poly(l-Ornithine)-Based Polymeric Micelles as pH-Responsive Macromolecular Anticancer Agents. Pharmaceutics, 2023; 15, 1307.

[9] Zheng M, Yang Q, Lu C, Wu X, Yan W, Liu D. Nanostructured organic photosensitizer aggregates in disease phototheranostics. Drug Discovery Today, 2023; 28, 103598.

[10] Zheng M, Wu X, Lu C, Zhang W, Tang S, Luo Y, Liu D. Polypept (o)ide-based bactericides: Weapons against antibiotic-resistant bacterial infections.  Mater.Today Chem. 2023; 27, 101270.

[11] Liu T, Pan C, Shi H, Huang T, Huang YL, Deng YY, Ni WX, Man WL. Cytotoxic cis-ruthenium (III) bis(amidine) complexes. Dalton Trans, 2023; 52, 8540-8548.

[12] Fang X, Huang W, Sun Q, Zhao Y, Sun R, Liu F, Huang D, Zhang Y, Gao F, Wang B. Melatonin attenuates cellular senescence and apoptosis in diabetic nephropathy by regulating STAT3 phosphorylation.Life Sci. 2023; 332:122108.

[13] Shafiq M, Bilal H, Permana B, Xu D, Cai G, Li X, Zeng M, Yuan Y, Jiao X, Yao F. Characterization of antibiotic resistance genes and mobile elements in extended-spectrum β-lactamase-producing Escherichia coli strains isolated from hospitalized patients in Guangdong, China. Journal of Applied Microbiology, 2023; 134(7): lxad125.

[14] Chen T, Ren C, Wong NK, Yan A, Sun C, Fan D, Luo P, Jiang X, Zhang L, Ruan Y, Li J, Wu X, Huo D, Huang J, Li X, Wu F, E Z, Cheng C, Zhang X, Wang Y, Hu C. The Holothuria leucospilota genome elucidates sacrificial organ expulsion and bioadhesive trap enriched with amyloid-patterned proteins. PNAS, 2023; 18;120(16): e2213512120.

[15] Wang W, Wong NK, Bok SL, Xu Y, Guo Y, Xu L, Zuo M, St Croix CM, Mao G, Kapralov A, Bayir H, Kagan VE, Yang D. Visualizing Cardiolipin in Situ with HKCL-1M, a Highly Selective and Sensitive Fluorescent Probe. Journal of American Chemical Society, 2023;145(20): 11311-11322.

[16] Yang D, Li Z, Zhang Y, Chen X, Liu M, Yang C. Design of Dual-Targeted pH-Sensitive Hybrid Polymer Micelles for Breast Cancer Treatment: Three Birds with One Stone. Pharmaceutics, 2023, 15, 1580.

[17] Huang W, Pan C, Huang Y, Huang T, Dong X, Chen Y, Shi H, Lau T, Man W, Ni W. (Salen)osmium (VI) nitrides catalyzed glutathione depletion in chemotherapy. Chinese Chemical Letters, 2023; 34108153.

[18] Yuan K, Huang R, Gong K, Xiao Z, Chen J, Cai S, Shen J, Xiong Z, Lin Z. Smartphone-based hand-held polarized light microscope for on-site pharmaceutical crystallinity characterization. Anal Bioanal Chem, 2023; 415(18): 4401-4410.

[19] Ye M, Li H, Luo H, Zhou Y, Luo W, Lin Z. Potential Antioxidative Activity of Homocysteine in Erythrocytes under Oxidative Stress. Antioxidants (Basel), 2022; 15; 12(1):202.

[20] Zheng L, Li X, Lian X, Xu R, Liu X, Xuan T, Zeng R, Ni WX, Luo B. Weakening Ligand-Liquid Affinity to Suppress the Desorption of Surface-Passivated Ligands from Perovskite Nanocrystals. Langmuir, 2022; 38, 15747-15755.

[21] Zhu X, Huang Y. Theoretical study on paramagnetic amino carbon nanotube as fluorouracil drug delivery system. Journal of Drug Delivery Science and Technology, 2022; 75: 103670.

[22] Chen W, Huang Y, Jiao X, Ye J, Lin Y, Yao F. Loss of erm(B)-Mediated rRNA Dimethylation and Restoration of Erythromycin Susceptibility in Erythromycin-Resistant Enterococci Following Induced Linezolid Resistance. Microb Drug Resist, 2022; 29(2): 51-58.

[23] Wang Q, Pan Y, Luo H, Zhang Y, Gao F, Wang J, Zheng J. Novel Approaches for the Solid-Phase Synthesis of Dihydroquinazoline-2(1 H)-One Derivatives and Biological eva luation as Potential Anticancer Agents. Molecules, 2022; 27(23): 8577.

[24] Yuan K, Beatriz Jurado-Sánchez, Alberto Escarpa. Nanomaterials meet surface-enhanced Raman scattering towards enhanced clinical diagnosis: a review. J Nanobiotechnology, 2022; 20(1): 537.

[25] Yu H, Li E, Liu S, Wu Z, Gao F, Zheng M. Identification of Signature Genes in the PD-1 Relative Gastric Cancer Using a Combined Analysis of Gene Expression and Methylation Data. Journal of Oncology, 2022:1-30.

[26] Yu H, Liu S, Wu Z, Gao F. GNAI2 Is a Risk Factor for Gastric Cancer: Study of Tumor Microenvironment (TME) and Establishment of Immune Risk Score (IRS). Oxidative medicine and cellular longevity, 2022; 1254367.

[27] Yang D, Chen X, Li Z, Yang C. Mechanistic Study of Release Characteristics of Two Active Ingredients in Transdermal Patch Containing Lidocaine-Flurbiprofen Ionic Liquid. Pharmaceutics, 2022; 14, 2158.

[28] Yang D, Fang L, Yang C. Roles of molecular interaction and mobility on loading capacity and release rate of drug-ionic liquid in long-acting controlled release transdermal patch. Journal of Molecular Liquids, 2022; 352: 118752.

[29] Zhao C, Chen Q, Li W, Zhang J, Yang C, Chen D. Multi-functional platelet membrane -camouflaged nanoparticles reduce neuronal apoptosis and regulate microglial phenotype during ischemic injury. Applied Materials Today, 2022; 27: 101412-101428.

[30] Huang C, Huang W, Ji P, Song F, Liu T, Li M, Guo H, Huang Y, Yu C, Wang C, Ni W. A Pyrazolate Osmium (VI) Nitride Exhibits Anticancer Activity through Modulating Protein Homeostasis in HepG2 Cells. International Journal of Molecular Sciences, 2022; 23(21), 12779.

[31] Jiang H, Xia Q, Zheng J, Bu J, Li R, Cai Z, Ling K. Mn2+modified black phosphorus nanosheets with enhanced DNA adsorption and affinity for robust sensing. Biosensors and Bioelectronics, 2022; 216: 114622.

[32] Li H, Zheng F, Zhang Y, Sun J, Gao F, Shi G. Resveratrol, novel application by preconditioning to attenuate myocardial ischemia/reperfusion injury in mice through regulate AMPK pathway and autophagy level.  J Cell Mol Med. 2022; 26(15):4216-4229.

[33] Li H, Yang D, Zhang Y, Zheng F, Gao F, Sun J, Shi G. Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury. Chin Med, 2022; 17(1) :73.

[34] Huang X, Wang B, Shen H, Huang D, Shi G. Farnesoid X receptor functions in cervical cancer via the p14 (ARF)- mouse double minute 2-p53 pathway. Mol Biol Rep, 2022; 49(5): 3617-3625.

[35] Shan Q, Fang Q, Tian Y. Reduction of excitatory synaptic transmission efficacy in the infralimbic prefrontal cortex potentially contributes to impairment of contextual fear memory extinction in aged mice. Journal of Gerontology A Biol Sci Med Sci, 2022; 13(14): 2084-2091.

[36] Shan Q, Fang Q, Tian Y. Evidence that GIRK Channels Mediate the DREADD-hM4Di Receptor Activation-Induced Reduction in Membrane Excitability of Striatal Medium Spiny Neurons. ACS Chemical Neuroscience, 2022; 13(14): 2084-2091.

[37] Shan Q, Yu X, Tian Y. Adolescent social isolation shifts the balance of decision-making strategy from goal-directed action to habitual response in adulthood via suppressing the excitatory neurotransmission onto the direct pathway of the dorsomedial striatum. Cerebral Cortex, 2022: bhac158.

[38] Huang YB, Ma ZG, Zheng C, Ma XK, Taylor DH, Gao M, Lukas RJ, Wu J. Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells. Acta Pharmacol Sin, 2022; 43(4): 889-896.

[39] Li S, Huang Y, Yu L, Ji X, Wu J. Impact of the cannabinoid system in Alzheimer's diseases. Curr Neuropharmacol, 2022; 21(3):715-726.

[40] Li Y, Yang XY, Jin N, Zhen C, Zhu SY, Chu WY, Zhang HH, Xu AP, Wu J, Wang MY, Zheng C. Activation of M3-AChR and IP3/Ca2+/PKC signaling pathways by pilocarpine increases glycine-induced currents in ventral horn neurons of the spinal cord. Neurosci Lett, 2022; 782:136690.

[41] Tao W, Zhao C, Lin G, Wang Q, Lv Q, Wang S, Chen Y. UPLC-ESI-QTOF-MS/MS. Analysis of the Phytochemical Compositions from Chaenomeles speciosa (Sweet) Nakai Fruits. J Chromatogr Sci, 2022; bmac002.

[42] Huang W and Chang W. Newcastle Disease Virus/HK84: next potential star for targeted immunotherapy of hepatocellular carcinoma? Journal of Clinical and Translational Hepatology. 2022; 10(2): 179-180.

[43] Shan Q, Hu Y, Chen S, Tian Y. Nucleus accumbens dichotomically controls social dominance in male mice. Neuropsychopharmacology, 2022; 47(3):776-787.

[44] Li X, Chen T, Wu X, Li Z, Zhang X, Jiang X, Luo P, Hu C, Wong NK, Ren C. Evolutionarily Ancient Caspase-9 Sensitizes Immune Effector Coelomocytes to Cadmium-Induced Cell Death in the Sea Cucumber, Holothuria leucospilota. Frontiers Immunology, 2022; 13:927880.

[45] Wei DW, Wong NK, Song Y, Zhang G, Wang C, Li J, Feng J. IS 26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics. mBio, 2022; 13(1): e0334021.

[46] Zhang Y, Mao F, Xiao S, Yu H, Xiang Z, Xu F, Li J, Wang L, Xiong Y, Chen M, Bao Y, Deng Y, Huo Q, Zhang L, Liu W, Li X, Ma H, Zhang Y, Mu X, Liu M, Zheng H, Wong NK, Yu Z.  Comparative Genomics Reveals Evolutionary Drivers of Sessile Life and Left-right Shell Asymmetry in Bivalves. Genomics Proteomics Bioinformatics, 2022; S1672-0229(22)00007-9.

[47] Yu X, Chen S, Shan Q. Depression in the Direct Pathway of the Dorsomedial Striatum Permits the Formation of Habitual Action. Cereb Cortex, 2021; 31(7):3551-3564.

[48] Tang Y, Huang S, Lin W, Wen K, Lin Z, Han M. Arachidonic Acid-Dependent Pathway Inhibition in Platelets: Its Role in Multiple Injury-Induced Coagulopathy and the Potential Mechanisms.  Shock, 2021; 55(1):121-127.

[49] Wang B, Li J, Bao M, Chen R, Li H, Lu B, Chen M, Huang D, Zhang Y, Gao F, Shi G. Melatonin Attenuates Diabetic Myocardial Microvascular Injury through Activating the AMPK/SIRT1 Signaling Pathway. Oxid Med Cell Longev. 2021:8882130.

[50] Niu Y, Fan S, Luo Q, Chen L, Huang D, Chang W, Qin W, Shi G. Interaction of hepatitis B virus X protein with the pregnane X receptor enhances the synergistic effects of aflatoxin B1 and hepatitis B virus in promoting hepatocarcinogenesis. J Clin Transl Hepatol, 2021; 9(4): 466-476.

[51] Niu Y, Chen L, Wu M, Huang W, Wu X, Huang D, Xie Y, Shi G. Partial abrogation of FXR-KNG1 signaling by carboxyl-terminal truncated HBx-C30 in hepatitis B virus-associated hepatocellular carcinoma. Virus Res., 2021; 293:198264.

[52] Xu C, Li R#, Wu J#. Effects of Yuanhu Zhitong tablets on alcohol-induced conditioned place preference in mice. Biomed Pharmacother, 2021; 133:110962.

[53] Cao M, Huang Z#, Zhou H, Lin J, Zhang D.Clinical and molecular genetic analysis of a Chinese family with hereditary elliptocytosis caused by a novel mutation in the EPB41 gene. J Clin Lab Anal., 2021; 35(6): e23781.

[54] Cai X, Sha F, Zhao C, Zheng Z, Zhao S, Zhu Z, Zhu H, Chen J, ChenY. Synthesis and anti-inflammatory activity of novel steroidal chalcones with 3β-pregnenolone ester derivatives in RAW 264.7 cells in vitro. Steroids. 2021; 171:108830.

[55] Zhao C, Wei M, Zheng Y, Tao W, Lv Q, Wang Q, Wang S, Chen Y.The Analyses of Chemical Components From Oldenlandia hedyotidea (DC.) Hand-Mazz and Anticancer Effects in vitro. Front Pharmacol, 2021; 12:624296.

[56] Huang X, Wang B, Chen R, Zhong S, Gao F, Zhang Y, Niu Y, Li C, Shi G.The Nuclear Farnesoid X Receptor Reduces p53 Ubiquitination and Inhibits Cervical Cancer Cell Proliferation. Front Cell Dev Biol., 2021;9:583146.

[57] Shen D, Cheng H, Cai B, Cai W, Wang B, Zhu Q, Wu Y, Liu M, Chen R, Gao F, Zhang Y, Niu Y, Shi G. N-n-Butyl haloperidol iodide ameliorates liver fibrosis and hepatic stellate cell activation in mice. Acta Pharmacol Sin., 2022; 43(1):133-145.

[58] Zheng M, Pan M, Zhang W Lin H, Wu S, Lu C, Tang S, Liu D, Cai J. Poly(L-lysine)-based nanomaterials for versatile biomedical applications: Current advances and perspectives. Bioact Mater, 2020; 6(7):1878-1909.

[59] Jiang H, Xia Q, Liu D, Ling K.Calcium-cation-doped polydopamine-modified 2D black phosphorus nanosheets as a robust platform for sensitive and specific biomolecule sensing. Anal Chim Acta, 2020; 1121:1-10.

[60] Zhang L, Song M, Zhang F, Yuan H, Chang W, Yu G, Niu Y. Accumulation of nicotinamide N-methyltransferase (NNMT) in cancer-associated fibroblasts: A potential prognostic and predictive biomarker for gastric carcinoma. J Histochem Cytochem, 2021; 69(3):165-176.

[61] Xing Y, Yan J, Niu Y.PXR: A Center of Transcriptional Regulation in Cancer. Acta Pharm Sin B, 2020;10(2):197-206.

[62] Huang S, Tang Y, Lin W, Wen K, Han W, Lin Z, Han M. Study on coagulation profiles and platelet function in trauma-induced coagulopathy caused by three types of injury. Injury, 2020;51(6):1312-1320.

[63] Zhou Z, Pan Q, Lv X, Yuan J, Zhang Y, Zhang M, Ke M, Mo X, Xie Y, Liu Y, Chen T, Liang M, Yin F, Liu L, Zhou Y, Qiao K, Liu R*, Li Z*, Wong NK*. Structural insights into the inhibition of bacterial RecA by naphthalene polysulfonated compounds. iScience,2020; 17;24(1):101952.

[64] Qiu Q, Li Y, Fan Z, Yao F#, Shen W, Sun J, Yuan Y, Chen J, Cai L, Xie Y, Liu K, Chen X, Jiao X. Gene Expression Analysis of Human Papillomavirus-Associated Colorectal Carcinoma. Biomed Res Int, 2020; 17;2020:5201587.

[65] Ma X, Chen K, Cui Y, Huang G, Nehme A, Zhang L, Li H, Wei J, Liong K, Liu Q, Shi L, Wu J*, Qiu S*. Depletion of microglia in developing cortical circuits reveals its critical role in glutamatergic synapse development, functional connectivity, and critical period plasticity. J Neurosci Res, 2020; 98(10):1968-1986.

[66] Li R, Xu C, Shen J, Ren Q, Chen D, Lin M, Huang R, Li C, Zhong R, Luo Z, Ji X*, Wu J*. 4-Methoxydalbergione is a potent inhibitor of human astroglioma U87 cells in vitro and in vivo. Acta Pharmacol Sin, 2021; 42(9):1507-1515.

[67] Ma Z, Jiang N, Huang Y, Ma X, Brek E, Gao M, Chang Y, Lukas R, Whiteaker P, Neisewander J, Wu J*. Cocaine potently blocks neuronal α3β4 nicotinic acetylcholine receptors in SH-SY5Y cells. Acta Pharmacol Sin, 2020; 41(2): 163-172.

[68] Pan M, Lu C, Zheng M, Zhou W, Song F, Chen W, Yao F, Liu D*, Cai J*. Unnatural amino acid-based star-shaped poly (L-ornithine) s as emerging long-term and biofilm-disrupting antimicrobial peptides to treat Pseudomonas aeruginosa-infected burn wounds. Adv Healthc Mater, 2020; 9(19): e2000647.

[69] Tian Y, Chen S, Shan Q. Charged residues at the pore extracellular half of the glycine receptor facilitate channel gating: a potential role played by electrostatic repulsion. J Physiol. 2020; 598, 20:4643-4661

[70] Huang W, Wang C, Liu T, Li Z, Pan C, Chen Y, Lian X, Man W*, Ni W*. A cytotoxic nitrido-osmium (VI) complex induces caspase-mediated apoptosis in HepG2 cancer cells. Dalton Trans, 2020; 49(47): 17173-17182.

[71] Han L, Shan Q. Pair of Residue Substitutions at the Outer Mouth of the Channel Pore Act as Inputs for a Boolean Logic “OR” Gate Based on the Glycine Receptor. ACS Chem Neurosci, 2020; 11(20): 3409-3417.

[72] Ji Y, Luo H, Li H, Lin Z, Luo W. Determination of plasma homocysteine with a UHPLC-MS/MS method: Application to analyze the correlation between plasma homocysteine and whole blood 5-methyltetrahydrofolate in healthy volunteers. 2020; 34(8): e4845.

[73] Zhang S, Liao W, Wu Q, Huang X, Qiu G. LINC00152 upregulates ZEB1 expression and enhances epithelial-mesenchymal transition and oxaliplatin resistance in esophageal cancer by interacting with EZH2. Cancer Cell International, 2020; 20(1).

[74] Zhang S, Zheng F, Zhang L, Huang Z, Huang X, Pan Z, Chen S, Xu C, Jiang Y, Gu S, Zhao C, Zhang Q, Shi G*. LncRNA HOTAIR-mediated MTHFR methylation inhibits 5-fluorouracil sensitivity in esophageal cancer cells. J Exp Clin Cancer Res, 2020; 39(1):131.

[75] Hong Z#, Lin M#, Zhang Y#, He Z, Zheng L, Zhong S. Role of Betaine in Inhibiting the Induction of RNA Pol III Gene Transcription and Cell Growth Caused by Alcohol. Chem Biol Interact, 2020; 11; 325:109129.

[76] Cai W, Zhong S, Zheng F, Zhang Y, Gao F, Xu H, Cai X, Lan J, Huang D, Shi G. Angiotensin II confers resistance to apoptosis in cardiac myofibroblasts through the AT1/ERK1/2/RSK1 pathway. IUBMB life, 2019; 71(2): 261-276.

[77] X. Cai, S. Zhao, Cai, J. Zheng, Z. Zhu, D. Wei, Z. Zheng, H. Zhu, Y. Chen, Synthesis and eva luation of novel D-ring substituted steroidal pyrazolines as potential anti-inflammatory agents. Steroids, 2019: 146: 70-78.

[78] Chen D, Gao F, Ma X, Eaton J.B., Huang Y, Gao M, Chang Y, Ma Z, Der-Ghazarian T, Neisewander J, Whiteaker P, WuJ, Su Q. Cocaine Directly Inhibits alpha6-Containing Nicotinic Acetylcholine Receptors in Human SH-EP1 Cells and Mouse VTA DA Neurons. Frontiers in pharmacology, 2019; 1072.

[79] Chen S, Han L, Shan Q. A loss-of-function mutation of an inhibitory zinc- and proton-binding site reduces channel blocker potency in the glycine receptor. Neuropharmacology, 2019; 153: 121-133.

[80] S. Chen, Y. Yi, T. Xia, Z. Hong, Y. Zhang, G. Shi, Z. He, S. Zhong, The influences of red wine in phenotypes of human cancer cells. Gene, 2019; 702:194-204.

[81] Y. Chen, H. Chen, G. Shi, M. Yang, F. Zheng, Z. Zheng, S. Zhang, S. Zhong, Ultra-performance liquid chromatography-tandem mass spectrometry quantitative profiling of tryptophan metabolites in human plasma and its application to clinical study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019; 1128 121745.

[82] Q. Chu, Y. Zhang, S. Zhong, F. Gao, Y. Chen, B. Wang, Z. Zhang, W. Cai, W. Li, F. Zheng, G. Shi, N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells. Oxidative medicine and cellular longevity, 2019;7417561.

[83] T. Du, J. Xiao, Z. Qiu, K. Wu, The effectiveness of intensity-modulated radiation therapy versus 2D-RT for the treatment of nasopharyngeal carcinoma: A systematic review and meta-analysis. PloS one, 2019: 14(7) e0219611.

[84] F. Gao, D. Chen, X. Ma, S. Sudweeks, J.T. Yorgason, M. Gao, D. Turner, J.B. Eaton, J.M. McIntosh, R.J. Lukas, P. Whiteaker, Y. Chang, S.C. Steffensen, J. Wu, Alpha6-containing nicotinic acetylcholine receptor is a highly sensitive target of alcohol. Neuropharmacology, 2019; 149: 45-54.

[85] C. Huang, Y. Zhang, S. Zhong, Alcohol Intake and Abnormal Expression of Brf1 in Breast Cancer. Oxidative medicine and cellular longevity, 2019: 4818106.

[86] Y. Huang, Y. Huang, M. Bao, S. Zheng, T. Du, K. Wu, Psychological resilience of women after breast cancer surgery: a cross-sectional study of associated influencing factors. Psychology, health & medicine, 2019; 24(7): 866-878.

[87] W. Li, G. Shi, How CaV1.2-bound verapamil blocks Ca (2+) influx into cardiomyocyte: Atomic level views. Pharmacological research, 2019;139: 153-157.

[88] W. Lin, W. Han, K. Wen, S. Huang, Y. Tang, Z. Lin, M. Han, The Alterations of Copper and Zinc Homeostasis in Acute Appendicitis and the Clinical Significance. Biological trace element research, 2019; 192(2): 116-122.

[89] Z. Ma, F. Gao, B. Larsen, M. Gao, Z. Luo, D. Chen, X. Ma, S. Qiu, Y. Zhou, J. Xie, Z.X. Xi, J. Wu, Mechanisms of cannabinoid CB2 receptor-mediated reduction of dopamine neuronal excitability in mouse ventral tegmental area. EBioMedicine, 2019; 42: 225-237.

[90] Q. Peng, L. Chen, S. Zhou, H. Li, J. Long, F. Yao, Y. Zhuang, Z. Zhang, Y. Huang, K. Duan, Co-existence of Citrobacter freundii exacerbated Pseudomonas aeruginosa infection in vivo. International journal of medical microbiology: IJMM; 2019: 151379.

[91] F. Tong, X. Tang, D. Liu, Phycocyanin/PEG-b-(PG-g-PEI) attenuated hepatic ischemia/reperfusion-induced pancreatic islet injury and enlarged islet functionality. International journal of nanomedicine, 2019; 14: 339-351.

[92] Q. Yang, Z. Li, W. Li, L. Lu, H. Wu, Y. Zhuang, K. Wu, X. Sui, Association of total testosterone, free testosterone, bioavailable testosterone, sex hormone-binding globulin, and hypertension; Medicine, 2019; 98(20): e15628.

[93] Q. Yang, X. Sui, J. Cao, C. Liu, S. Zheng, M. Bao, Y. Huang, K. Wu. Effects of Exposure to Bisphenol A during Pregnancy on the Pup Testis Function, International journal of endocrinology (2019) 2019 6785289.

[94] S. Zhou, Y. Zhuang, X. Zhu, F. Yao, H. Li, H. Li, X. Zou, J. Wu, H. Zhou, G. Nuer, Y. Huang, S. Li, Q. Peng. YhjX Regulates the Growth of Escherichia coli in the Presence of a Subinhibitory Concentration of Gentamicin and Mediates the Adaptive Resistance to Gentamicin. Frontiers in microbiology; 2019; 10: 1180.

[95] D.J. Chen, F.F. Gao, X.K. Ma, G.G. Shi, Y.B. Huang, Q.X. Su, S. Sudweeks, M. Gao, T. Dharshaun, J.B. Eaton, Y.C. Chang, J.M. McIntosh, R.J. Lukas, P. Whiteaker, S.C. Steffensen, J. Wu. Pharmacological and functional comparisons of alpha6/alpha3beta2beta3-nAChRs and alpha4beta2-nAChRs heterologously expressed in the human epithelial SH-EP1 cell line. Acta pharmacologica Sinica, 2018; 39(10): 1571-1581.

[96] Y.J. Choi, D. Zhou, A.C.S. Barbosa, Y. Niu, X. Guan, M. Xu, S. Ren, T.D. Nolin, Y. Liu, W. Xie. Activation of Constitutive Androstane Receptor Ameliorates Renal Ischemia-Reperfusion-Induced Kidney and Liver Injury. Molecular pharmacology, 2018; 93(3) :239-250.

[97] M. Han, S. Ding, Y. Zhang, Z. Lin, K. Li. Serum Copper Homeostasis in Hypertensive Intracerebral Hemorrhage and its Clinical Significance. Biological trace element research, 2018; 185(1): 56-62.

[98] Y. He, L. Peng, W. Zhang, C. Liu, Q. Yang, S. Zheng, M. Bao, Y. Huang, K. Wu. Adipose tissue levels of polybrominated diphenyl ethers and breast cancer risk in Chinese women: A case-control study. Environmental research, 2018;167: 160-168.

[99] X. Hong, Z. Yu, Z. Chen, H. Jiang, Y. Niu, Z. Huang, High molecular weight fibroblast growth factor 2 induces apoptosis by interacting with complement component 1 Q subcomponent-binding protein in vitro. Journal of cellular biochemistry, 2018; 119(11): 8807-8817.

[100] Y. Huang, H. Xu, W. Au, C. Xu, K. Wu.  Involvement of family environmental, behavioral, and social functional factors in children with attention-deficit/hyperactivity disorder. Psychology research and behavior management, 2018; 11: 447-457.

[101] H. Jiang, F.R. Li, W. Li, X. Lu, K. Ling. Multiplexed determination of intracellular messenger RNA by using a graphene oxide nanoprobe modified with target-recognizing fluorescent oligonucleotides. Mikrochimica acta, 2018; 185(12): 552.

[102] G.W. Liang, Y.C. Chen, Y. Wang, H.M. Wang, X.Y. Pan, P.H. Chen, Q.X. Niu. Interaction between Saikosaponin D, Paeoniflorin, and Human Serum Albumin. Molecules (Basel, Switzerland), 2018; 23(2).

[103] K. Ling, H. Jiang, X. Huang, Y. Li, J. Lin, F.R. Li. Direct chemiluminescence detection of circulating microRNAs in serum samples using a single-strand specific nuclease-distinguishing nucleic acid hybrid system. Chemical communications (Cambridge, England), 2018; 54(15): 1909-1912.

[104] H. Luo, K. Wood, F.D. Shi, F. Gao, Y. Chang. Suramin is a novel competitive antagonist selective to alpha1beta2gamma2 GABAA over rho1 GABAC receptors. Neuropharmacology, 2018; 141: 148-157.

[105] J. Shi, J. Qian, H. Li, H. Luo, W. Luo, Z. Lin. Renal tubular epithelial cells injury induced by mannitol and its potential mechanism. Renal failure, 2018; 40(1): 85-91.

[106] T. Sun, Y. Zhang, S. Zhong, F. Gao, Y. Chen, B. Wang, W. Cai, Z. Zhang, W. Li, S. Lu, F. Zheng, G. Shi. N-n-Butyl Haloperidol Iodide, a Derivative of the Anti-psychotic Haloperidol, Antagonizes Hypoxia/Reoxygenation Injury by Inhibiting an Egr-1/ROS Positive Feedback Loop in H9c2 Cells. Frontiers in pharmacology, 2018; 9: 19.

[107] D.C. Wei, Y. Pan, H. Wang, W.J. Xu, C. Chen, J.H. Zheng, D. Cai. Synthesis of substituted aromatic heterocyclic sulfonyl hydrazone compounds and in vitro anti-hepatoma activity: preliminary results. European review for medical and pharmacological sciences, 2018; 22(14) :4720-4729.

[108] Z. Yan, D. Shen, J. Liao, Y. Zhang, Y. Chen, G. Shi, F. Gao. Hypoxia Suppresses TGF-B1-Induced Cardiac Myocyte Myofibroblast Transformation by Inhibiting Smad2/3 and Rhoa Signaling Pathways. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018; 45(1): 250-257.

[109] S. Zhang, Q. Zhang, G. Shi, J. Yin. MiR-182-5p regulates BCL2L12 and BCL2 expression in acute myeloid leukemia as a potential therapeutic target. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018; 97: 1189-1194.

[110] X. Bai, P. Yang, Q. Zhou, B. Cai, M. Buist-Homan, H. Cheng, J. Jiang, D. Shen, L. Li, X. Luo, K.N. Faber, H. Moshage, G. Shi. The protective effect of the natural compound hesperetin against fulminant hepatitis in vivo and in vitro. British journal of pharmacology, 2017; 174(1): 41-56.

[111] D.J. Chen, M. Gao, F.F. Gao, Q.X. Su, J. Wu. Brain cannabinoid receptor 2: expression, function and modulation. Acta pharmacologica Sinica, 2017; 38(3): 312-316.

[112] Z. Fang, Y. Yi, G. Shi, S. Li, S. Chen, Y. Lin, Z. Li, Z. He, W. Li, S. Zhong. Role of Brf1 interaction with ERalpha, and significance of its overexpression, in human breast cancer, Molecular oncology, 2017; 11(12): 1752-1767.

[113] Y. He, L. Peng, Y. Huang, C. Liu, S. Zheng, K. Wu. Blood cadmium levels associated with short distant metastasis-free survival time in invasive breast cancer. Environmental science and pollution research international, 2017; 24(36): 28055-28064.

[114] Y. He, L. Peng, Y. Huang, X. Peng, S. Zheng, C. Liu, K. Wu. Association of breast adipose tissue levels of polychlorinated biphenyls and breast cancer development in women from Chaoshan, China. Environmental science and pollution research international, 2017; 24(5): 4778-4790.

[115] C. Lu, X. Li, W. Xia, S. Lu, H. Luo, D. Ye, Y. Zhang, D. Liu. Poly(epsilon-benzyloxycarbonyl-L-lysine)-grafted branched polyethylenimine as efficient nanocarriers for indomethacin with enhanced oral bioavailability and anti-inflammatory efficacy. Acta biomaterialia, 2017; 49: 434-443.

[116] Y. Niu, M. Xu, B.L. Slagle, H. Huang, S. Li, G.L. Guo, G. Shi, W. Qin, W. Xie. Farnesoid X receptor ablation sensitizes mice to hepatitis b virus X protein-induced hepatocarcinogenesis. Hepatology (Baltimore, Md.), 2017; 65(3): 893-906.

[117] H.M. Shen, C. Chen, J.Y. Jiang, Y.L. Zheng, W.F. Cai, B. Wang, Z. Ling, L. Tang, Y.H. Wang, G.G. Shi. The N-butyl alcohol extract from Hibiscus rosa-sinensis L. flowers enhances healing potential on rat excisional wounds. Journal of ethnopharmacology, 2017; 198: 291-301.

[118] L. Tang, Y. Chen, Z. Jiang, S. Zhong, W. Chen, F. Zheng, G. Shi. Purification, partial characterization and bioactivity of sulfated polysaccharides from Grateloupia livida. International journal of biological macromolecules, 2017; 94(Pt A): 642-652.

[119] F. Tong, X. Tang, L. Luo, X. Li, W. Xia, C. Lu, D. Liu. Sustained delivery of insulin-loaded block copolymers: Potential implications on renal ischemia/reperfusion injury in diabetes mellitus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017; 91: 534-545.

[120] Z. Tong, W. Wang, W. Luo, J. Lv, H. Li, H. Luo, J. Jia, R. He. Urine Formaldehyde Predicts Cognitive Impairment in Post-Stroke Dementia and Alzheimer's Disease. Journal of Alzheimer's disease JAD, 2017; 55(3): 1031-1038.

[121] H. Wang, J. Zheng, W. Xu, C. Chen, D. Wei, W. Ni, Y. Pan. A New Series of Cytotoxic Pyrazoline Derivatives as Potential Anticancer Agents that Induce Cell Cycle Arrest and Apoptosis. Molecules (Basel, Switzerland), 2017; 22(10).

[122] Z. Wu, P. Wu, X. Zuo, N. Yu, Y. Qin, Q. Xu, S. He, B. Cen, W. Liao, A. Ji. LncRNA-N1LR Enhances Neuroprotection Against Ischemic Stroke Probably by Inhibiting p53 Phosphorylation. Molecular neurobiology, 2017; 54(10): 7670-7685.

[123] W. Xu, Y. Pan, H. Wang, H. Li, Q. Peng, D. Wei, C. Chen, J. Zheng. Synthesis and eva luation of New Pyrazoline Derivatives as Potential Anticancer Agents in HepG-2 Cell Line. Molecules (Basel, Switzerland), 2017; 22(3).

[124] Y. Yi, C. Huang, Y. Zhang, S. Tian, J. Lei, S. Chen, G. Shi, Z. Wu, N. Xia, S. Zhong. Exploring a common mechanism of alcohol-induced deregulation of RNA Pol III genes in liver and breast cells. Gene, 2017; 626: 309-318.

[125] J. Zhang, Y. Huang, C. Wang, Y. He, S. Zheng, K. Wu. Efficacy and safety of endocrine monotherapy as first-line treatment for hormone-sensitive advanced breast cancer: A network meta-analysis. Medicine, 2017; 96(33): e7846.

[126] S. Zheng, C. Liu, Y. Huang, M. Bao, Y. Huang, K. Wu. Effects of 2,2',4,4'-tetrabromodiphenyl ether on neurobehavior and memory change and bcl-2, c-fos, grin1b and lingo1b gene expression in male zebrafish (Danio rerio). Toxicology and applied pharmacology, 2017: 333: 10-16.

[127] C. Cai, Y. Chen, S. Zhong, Y. Zhang, J. Jiang, H. Xu, G. Shi. Synergistic Effect of Compounds from a Chinese Herb: Compatibility and Dose Optimization of Compounds from N-Butanol Extract of Ipomoea stolonifera. Scientific reports, 2016; 6: 27014.

[128] Y.C. Chen, H.M. Wang, Q.X. Niu, D.Y. Ye, G.W. Liang, Binding between Saikosaponin C and Human Serum Albumin by Fluorescence Spectroscopy and Molecular Docking. Molecules (Basel, Switzerland), 2016; 21(2): 153.

[129] S. Li, H. Wang, D.D. Li, X.D. Zhang, Y.F. Wang, J.F. Xie, J.Y. Wang, Y.P. Tian, W.X. Ni, Y. Xie. Siloxene nanosheets: a metal-free semiconductor for water splitting. Journal of Materials Chemistry A, 2016; 4(41): 15841-15844.

[130] Z. Lin, Q. Zhang, W. Luo. Angiogenesis inhibitors as therapeutic agents in cancer: Challenges and future directions. European journal of pharmacology, 2016; 793: 76-81.

[131] K.T. Liu, W.S. Zhang, F.C. Lei, L. Liang, B.C. Gu, Y.F. Sun, B.J. Ye, W.X. Ni, Y. Xie. Nitrogen-doping induced oxygen divacancies in freestanding molybdenum trioxide single-layers boosting electrocatalytic hydrogen evolution. Nano Energy, 2016; 30: 810-817.

[132] B. Lu, B. Wang, S. Zhong, Y. Zhang, F. Gao, Y. Chen, F. Zheng, G. Shi. N-n-butyl haloperidol iodide ameliorates hypoxia/reoxygenation injury through modulating the LKB1/AMPK/ROS pathway in cardiac microvascular endothelial cells. Oncotarget, 2016; 7(23): 34800-10.

[133] S. Lu, Y. Zhang, S. Zhong, F. Gao, Y. Chen, W. Li, F. Zheng, G. Shi. N-n-butyl Haloperidol Iodide Protects against Hypoxia/Reoxygenation Injury in Cardiac Microvascular Endothelial Cells by Regulating the ROS/MAPK/Egr-1 Pathway. Frontiers in pharmacology, 2016;7: 520.

[134] W. Luo, B. Liu, Y. Zhou. The endothelial cyclooxygenase pathway: Insights from mouse arteries. European journal of pharmacology, 2016; 780: 148-58.

[135] S. Qamar, F.C. Lei, L. Liang, S. Gao, K.T. Liu, Y.F. Sun, W.X. Ni, Y. Xie. Ultrathin TiO2 flakes optimizing solar light driven CO2 reduction. Nano Energy, 2016; 26: 692-698.

[136] G.Z. Sun, F.F. Gao, Z.M. Zhao, H. Sun, W. Xu, L.W. Wu, Y.C. He. Endoplasmic reticulum stress-induced apoptosis in the penumbra aggravates secondary damage in rats with traumatic brain injury. Neural regeneration research, 2016; 11(8): 1260-6.

[137] R.W.Y. Sun, R.F. Xu, H.Q. Song, C. Saint-Germain, M. Zhang, W.X. Ni, C.X. Chen, C. Hemmert, H. Gornitzka, D. Li. A gold(I)-pyrazolato complex as a switch-on luminescent probe for cysteine: in situ formation of fluorescent nanoparticles and rose-like microspheres. Inorganic Chemistry Frontiers, 2016; 3(11): 1406-1410.

[138] F. Tong, L. Luo, D. Liu. Effect of Intervention in Mast Cell Function Before Reperfusion on Renal Ischemia-Reperfusion Injury in Rats. Kidney & blood pressure research, 2016: 41(3): 335-44.

[139] F. Tong, X. Tang, X. Li, W. Xia, D. Liu. The effect of insulin-loaded linear poly (ethylene glycol)-brush-like poly(l-lysine) block copolymer on renal ischemia/reperfusion-induced lung injury through downregulating hypoxia-inducible factor. International journal of nanomedicine, 2016: 11: 1717-30.

[140] Q. Zhang, Z. Lin, X. Yin, L. Tang, H. Luo, H. Li, Y. Zhang, W. Luo. In vitro and in vivo study of hydralazine, a potential anti-angiogenic agent. European journal of pharmacology, 2016, 779: 138-46.

[141] Y. Zhang, W. Lu, M. Han, H. Li, H. Luo, W. Li, W. Luo, Z. Lin. Biphasic Effects of Copper on Rat Learning and Memory in the Morris Water Maze. Annals of clinical and laboratory science, 2016; 46(4): 346-52.

[142] Y. Zhuang, W. Chen, F. Yao, Y. Huang, S. Zhou, H. Li, Z. Zhang, C. Cai, Y. Gao, Q. Peng. Short-Term Pretreatment of Sub-Inhibitory Concentrations of Gentamycin Inhibits the Swarming Motility of Escherichia Coli by Down-Regulating the Succinate Dehydrogenase Gene. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology,2016; 39(4): 1307-16.

[143] W. Chen, J. Sheng, J. Guo, F. Gao, X. Zhao, J. Dai, G. Wang, K. Li. Tumor necrosis factor-alpha enhances voltage-gated Na (+) currents in primary culture of mouse cortical neurons. Journal of neuroinflammation, 2015; 12: 126.

[144] Y.C. Chen, W. Zhu, S.P. Zhong, F.C. Zheng, F.F. Gao, Y.M. Zhang, H. Xu, Y.S. Zheng, G.G. Shi. Characterization and bioactivity of novel calcium antagonists - N-methoxy-benzyl haloperidol quaternary ammonium salt. Oncotarget, 2015; 6(41): 43759-69.

[145] Y. Huang, W. Ni, Y. Chen, X. Wang, J. Zhang, K. Wu. Levels and risk factors of antimony contamination in human hair from an electronic waste recycling area, Guiyu, China. Environmental science and pollution research international, 2015; 22(9): 7112-71.

[146] Huang, X.L. Wang, J.W. Zhang, K.S. Wu. Impact of endocrine-disrupting chemicals on reproductive function in zebrafish (Danio rerio). Reproduction in domestic animals = Zuchthygiene, 2015; 50(1): 1-6.

[147] Y. Huang, G. Zhu, L. Peng, W. Ni, X. Wang, J. Zhang, K. Wu. Effect of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on sexual behaviors and reproductive function in male zebrafish (Danio rerio). Ecotoxicology and environmental safety, 2015; 111: 102-8.

[148] C. Liu, H. Yu, Y. Zhang, D. Li, X. Xing, L. Chen, X. Zeng, D. Xu, Q. Fan, Y. Xiao, W. Chen, Q. Wang. Upregulation of miR-34a-5p antagonizes AFB1-induced genotoxicity in F344 rat liver. Toxicon: official journal of the International Society on Toxinology, 2015; 106: 46-56.

[149] C. Lu, F. Tong, X. Tang, X. Zeng, D. Liu. Poly(L-lysine)-based cylindrical copolypeptide brushes as potential drug and gene carriers. Journal of controlled release: official journal of the Controlled Release Society, 2015: 213 e24-5.

[150] L. Peng, Y. Huang, J. Zhang, Y. Peng, X. Lin, K. Wu, X. Huo, Cadmium exposure and the risk of breast cancer in Chaoshan population of southeast China. Environmental science and pollution research international, 2015; 22(24): 19870-8.

[151] L. Peng, X. Wang, X. Huo, X. Xu, K. Lin, J. Zhang, Y. Huang, K. Wu. Blood cadmium burden and the risk of nasopharyngeal carcinoma: a case-control study in Chinese Chaoshan population. Environmental science and pollution research international, 2015; 22(16): 12323-31.

[152] Q. Shan, M.J. Christie, B.W. Balleine, Plasticity in striatopallidal projection neurons mediates the acquisition of habitual actions. The European journal of neuroscience, 2015; 42(4): 2097-104.

[153] Z. Tong, C. Han, M. Qiang, W. Wang, J. Lv, S. Zhang, W. Luo, H. Li, H. Luo, J. Zhou, B. Wu, T. Su, X. Yang, X. Wang, Y. Liu, R. He. Age-related formaldehyde interferes with DNA methyltransferase function, causing memory loss in Alzheimer's disease. Neurobiology of aging, 2015; 36(1): 100-10.

[154] B. Wang, S. Zhong, F. Zheng, Y. Zhang, F. Gao, Y. Chen, B. Lu, H. Xu, G. Shi. N-n-butyl haloperidol iodide protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy. Oncotarget, 2015; 6(28): 24709-21.

[155] D. Ye, Z. Jiang, F. Zheng, H. Wang, Y. Zhang, F. Gao, P. Chen, Y. Chen, G. Shi. Optimized Extraction of Polysaccharides from Grateloupia livida (Harv.) Yamada and Biological Activities. Molecules (Basel, Switzerland), 2015; 20(9): 16817-32.

[156] J. Zhang, Y. Huang, X. Wang, K. Lin, K. Wu. Environmental Polychlorinated Biphenyl Exposure and Breast Cancer Risk: A Meta-Analysis of Observational Studies. PloS one, 2015; 10(11): e0142513.

[157] Y. Zhang, H. Liao, S. Zhong, F. Gao, Y. Chen, Z. Huang, S. Lu, T. Sun, B. Wang, W. Li, H. Xu, F. Zheng, G. Shi. Effect of N-n-butyl haloperidol iodide on ROS/JNK/Egr-1 signaling in H9c2 cells after hypoxia/reoxygenation. Scientific reports, 2015; 5: 11809.

[158] J. Zhu, X. Zhang, G. Shi, K. Yi, X. Tan. Atrial Fibrillation Is an Independent Risk Factor for Hospital-Acquired Pneumonia. PloS one, 2015; 10(7): e0131782.

[159] W. Zhuang, K. Wu, Y. Wang, H. Zhu, Z. Deng, L. Peng, G. Zhu. Association of serum bisphenol-A concentration and male reproductive function among exposed workers. Archives of environmental contamination and toxicology, 2015; 68(1): 38-45.

[160] C. Cai, Y. Chen, S. Zhong, B. Ji, J. Wang, X. Bai, G. Shi. Anti-inflammatory activity of N-butanol extract from Ipomoea stolonifera in vivo and in vitro. PloS one, 2014; 9(4): e95931.

[161] Y.P. Huang, F.F. Gao, B. Wang, F.C. Zheng, Y.M. Zhang, Y.C. Chen, Z.Q. Huang, Y.S. Zheng, S.P. Zhong, G.G. Shi. N-n-butyl haloperidol iodide inhibits H2O2-induced Na+/Ca2+-exchanger activation via the Na+/H+ exchanger in rat ventricular myocytes. Drug design, development and therapy, 2014: 8: 1257-67.

[162] W.X. Ni, Y.M. Qiu, M. Li, J. Zheng, R.W. Sun, S.Z. Zhan, S.W. Ng, D. Li. Metallophilicity-driven dynamic aggregation of a phosphorescent gold(I)-silver(I) cluster prepared by solution-based and mechanochemical approaches. Journal of the American Chemical Society, 2014; 136(27): 9532-5.

[163] Y. Niu, Z. Wang, H. Huang, S. Zhong, W. Cai, Y. Xie, G. Shi. Activated pregnane X receptor inhibits cervical cancer cell proliferation and tumorigenicity by inducing G2/M cell-cycle arrest. Cancer letters, 2014; 347(1): 88-97.

[164] Q. Shan, M. Ge, M.J. Christie, B.W. Balleine. The acquisition of goal-directed actions generates opposing plasticity in direct and indirect pathways in dorsomedial striatum. The Journal of neuroscience: the official journal of the Society for Neuroscience, 2014: 34(28) 9196-201.

[165] Y. Wang, S. Liu, Y. Zhang, C. Bi, Y. Xiao, R. Lin, B. Huang, D. Tian, S. Ying, M. Su, Helicobacter pylori infection and gastric cardia cancer in Chaoshan region, Microbes and infection, 2014; 16(10): 840-4.

[166] R. Yuan, F. Zheng, S. Zhong, X. Tao, Y. Zhang, F. Gao, F. Yao, J. Chen, Y. Chen, G. Shi. Self-assembled nanoparticles of glycyrrhetic acid-modified pullulan as a novel carrier of curcumin. Molecules (Basel, Switzerland), 2014; 19(9): 13305-18.

[167] L. Han, S. Talwar, Q. Wang, Q. Shan, J.W. Lynch. Phosphorylation of alpha3 glycine receptors induces a conformational change in the glycine-binding site. ACS chemical neuroscience, 2013; 4(10): 1361-70.

[168] Y. Zhang, G. Chen, S. Zhong, F. Zheng, F. Gao, Y. Chen, Z. Huang, W. Cai, W. Li, X. Liu, Y. Zheng, H. Xu, G. Shi. N-n-butyl haloperidol iodide ameliorates cardiomyocytes hypoxia/reoxygenation injury by extracellular calcium-dependent and -independent mechanisms. Oxidative medicine and cellular longevity, 2013; 912310.

[169] Y. Huang, F. Gao, Y. Zhang, Y. Chen, B. Wang, Y. Zheng, G. Shi. N-n-Butyl haloperidol iodide inhibits the augmented Na+/Ca2+ exchanger currents and L-type Ca2+ current induced by hypoxia/reoxygenation or H2O2 in cardiomyocytes. Biochemical and biophysical research communications, 2012; 421(1): 86-90.

[170] Y.M. Zhang, C.Y. Wang, F.C. Zheng, F.F. Gao, Y.C. Chen, Z.Q. Huang, Z.Y. Xia, M.G. Irwin, W.Q. Li, X.P. Liu, Y.S. Zheng, H. Xu, G.G. Shi. Effects of N-n-butyl haloperidol iodide on the rat myocardial sarcoplasmic reticulum Ca (2+)-ATPase during ischemia/reperfusion. Biochemical and biophysical research communications, 2012; 425(2): 426-30.

[171] J. Zheng, Y. Chen, F. Yao, W. Chen, G. Shi. Chemical composition and antioxidant/antimicrobial activities in supercritical carbon dioxide fluid extract of Gloiopeltis tenax. Marine drugs, 2012; 10(12): 2634-47.

[172] X. Bai, Y. Chen, W. Chen, H. Lei, F. Gao, Y. Qin, J. Zheng, G. Shi. The effect of black coral extraction on acute lung inflammation induced by cigarette smoke in mice. Experimental lung research, 2011; 37(10): 627-32.

[173] X. Bai, Y. Chen, W. Chen, H. Lei, G. Shi. Volatile constituents, inorganic elements and primary screening of bioactivity of black coral cigarette holders. Marine drugs, 2011; 9(5): 863-78.

[174] Y. Chen, J. Zheng, F. Zheng, J. Wang, Y. Zhang, F. Gao, Z. Huang, G. Shi. Design, synthesis, and pharmacological eva luation of haloperidol derivatives as novel potent calcium channel blockers with vasodilator activity. PloS one, 2011; 6(11): e27673.

[175] J.F. Xiao, C.Y. Wang, Y.P. Huang, J.X. Shen, F.F. Gao, Z.Q. Huang, Y.S. Zheng, G.G. Shi. N-n-butyl haloperidol iodide preserves cardiomyocyte calcium homeostasis during hypoxia/ischemia. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011; 27(5): 433-42.

[176] F.F. Gao, S.Y. Hao, Z.Q. Huang, Y.M. Zhang, Y.Q. Zhou, Y.C. Chen, X.P. Liu, G.G. Shi. Cardiac electrophysiological and antiarrhythmic effects of N-n-butyl haloperidol iodide. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010; 25(4-5): 433-42.

[177] J.Z. Wang, C.Y. Cai, Y.M. Zhang, J.H. Zheng, Y.C. Chen, W.Q. Li, G.G. Shi. N-n-Butyl haloperidol iodide protects against hypoxia/reoxygenation-induced cardiomyocyte injury by modulating protein kinase C activity. Biochemical pharmacology, 2010; 79(10): 1428-36.

[178] Y. Zhou, G. Shi, J. Zheng, Z. Huang, F. Gao, Y. Zhang, F. Guo, Q. Jia, Y. Zheng. The protective effects of Egr-1 antisense oligodeoxyribonucleotide on cardiac microvascular endothelial injury induced by hypoxia-reoxygenation. Biochemistry and cell biology = Biochimie et biologie cellulaire, 2010; 88(4): 687-95.

[179] Y. Zhou, Y. Zhang, F. Gao, F. Guo, J. Wang, W. Cai, Y. Chen, J. Zheng, G. Shi. N-n-butyl haloperidol iodide protects cardiac microvascular endothelial cells from hypoxia/reoxygenation injury by down-regulating Egr-1 expression. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010; 26(6): 839-48.

[180] Y. Chen, J. Zheng, Y. Zhang, J. Wang, Q. Liu, Z. Huang, F. Gao, Y. Zhou, G. Shi. N-4-tert-butyl benzyl haloperidol chloride suppresses Ca2+-dependent Egr-1 expression and subsequently inhibits vascular smooth muscle cell proliferation induced by angiotensin II. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009; 23(4-6): 295-304.

[181] F.F. Gao, Q.Y. Jia, F.X. Guo, Y.M. Zhang, Z.Q. Huang, Y.Q. Zhou, Y.C. Chen, G.G. Shi. Egr-1, a central and unifying role in cardioprotection from ischemia-reperfusion injury? Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009; 24(5-6): 519-26.

[182] Z. Huang, H. Li, F. Guo, Q. Jia, Y. Zhang, X. Liu, G. Shi. Egr-1, the potential target of calcium channel blockers in cardioprotection with ischemia/reperfusion injury in rats. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009; 24(1-2): 17-24.

[183] F.F. Gao, G.G. Shi, Y.Q. Zhou, X.P. Liu. Reformative cannula electrodes for His bundle electrogram recording in isolated rat hearts. The Chinese journal of physiology, 2008; 51(2): 116-9.

[184] Y. Zhang, G. Shi, J. Zheng, Y. Lv, P. Gao, Z. Huang, F. Gao, Y. Zhou. The protective effect of Egr-1 antisense oligodeoxyribonucleotide on myocardial injury induced by ischemia-reperfusion and hypoxia-reoxygenation. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology, 2008; 22(5-6): 645-52.

[185] Z. Huang, G. Shi, F. Gao, Y. Zhang, X. Liu, T.A. Christopher, B. Lopez, X. Ma. Effects of N-n-butyl haloperidol iodide on L-type calcium channels and intracellular free calcium in rat ventricular myocytes. Biochemistry and cell biology = Biochimie et biologie cellulaire, 2007; 85(2): 182-8.

[186] F. Yao, Y. Qian, S. Chen, P. Wang, Y. Huang. Incidence of extended-spectrum beta-lactamases and characterization of integrons in extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolated in Shantou, China. Acta biochimica et biophysica Sinica, 2007; 39(7:) 527-32.

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[188] Y.M. Zhang, G.G. Shi, Z. Tang, J.H. Zheng, W.Q. Li, F.X. Guo, Q.Y. Jia. Effects of N-n-butyl haloperidol iodide on myocardial ischemia/reperfusion injury and Egr-1 expression in rat. Acta biochimica et biophysica Sinica, 2006; 38(6): 435-41.

[189] F.F. Gao, G.G. Shi, J.H. Zheng, B. Liu. Protective effects of N-n-butyl haloperidol iodide on myocardial ischemia-reperfusion injury in rabbits. The Chinese journal of physiology, 2004; 47(2): 61-6.

[190] Z.Q. Huang, G.G. Shi, J.H. Zheng, B. Liu. Effects of N-n-butyl haloperidol iodide on rat myocardial ischemia and reperfusion injury and L-type calcium current. Acta pharmacologica Sinica, 2003; 24(8): 757-63.

[191] G.G. Shi, H. Fang, J.H. Zheng. Quaternary ammonium salt derivative of haloperidol inhibits KCl-induced calcium increase in rat aortic smooth muscle cells. Acta pharmacologica Sinica, 2001; 22(9): 837-40.